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Chemical structure of MDL 100907

GC10051

MDL 100907

Also known as (R)-(2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol

MDL 100907 is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0·36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors

ChemicalCAS139290-65-6MW373.46FormulaC22H28FNO3
CAS number
139290-65-6
Molecular weight
373.46
Formula
C22H28FNO3
Solubility
DMF: 25 mg/ml,DMF:PBS(pH 7·2)(1:1): 0·5 mg/ml,DMSO: 15 mg/ml,Ethanol: 20 mg/ml
InChIKey
HXTGXYRHXAGCFP-OAQYLSRUSA-N
Catalogue number
GC10051
Brand
GLPBIO
Computed properties PubChem CID 5311271 · XLogP 3.9 · TPSA 41.9 Ų · H-bond donors 1
XLogP
3.9
TPSA
41.9 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
27

SMILES COC1=CC=CC(=C1OC)[C@@H](C2CCN(CC2)CCC3=CC=C(C=C3)F)O

Computed descriptors from PubChem (CID 5311271), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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