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Chemical structure of Cobimetinib

GC10033

Cobimetinib

Also known as [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone

A potent, orally available MEK1 inhibitor

ChemicalCAS934660-93-2MW531.31FormulaC21H21F3IN3O2
CAS number
934660-93-2
Molecular weight
531.31
Formula
C21H21F3IN3O2
Solubility
≥ 26·55 mg/mL in DMSO, ≥ 33·53 mg/mL in EtOH with gentle warming
InChIKey
BSMCAPRUBJMWDF-KRWDZBQOSA-N
Catalogue number
GC10033
Brand
GLPBIO
Computed properties PubChem CID 16222096 · XLogP 3.9 · TPSA 64.6 Ų · H-bond donors 3
XLogP
3.9
TPSA
64.6 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
30

SMILES C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O

Computed descriptors from PubChem (CID 16222096), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.