GB40423
YW2065
Also known as 1-(2-bromophenyl)-5-methyl-N-quinolin-2-ylpyrazole-4-carboxamide
The dual-functional compound YW2065 is a potent inhibitor of the Wnt/β-catenin signaling pathway (IC50 value of 2·3 nM) and an AMPK activator· YW2065 may achieve its dual activities through the mechanism of A1in-1 stabilization· YW2065 demonstrated favorable PK properties and suppressed tumor growth in a xenograft mouse model
ChemicalCAS2131223-85-1MW407.26FormulaC20H15BrN4O
- CAS number
- 2131223-85-1
- Molecular weight
- 407.26
- Formula
- C20H15BrN4O
- InChIKey
- ATYUYECWVYSPBS-UHFFFAOYSA-N
- Catalogue number
- GB40423
- Brand
- GLPBIO
Computed properties PubChem CID 137375527 · XLogP 4.4 · TPSA 59.8 Ų · H-bond donors 1
- XLogP
- 4.4
- TPSA
- 59.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 26
SMILES CC1=C(C=NN1C2=CC=CC=C2Br)C(=O)NC3=NC4=CC=CC=C4C=C3
Computed descriptors from PubChem (CID 137375527), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il