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Chemical structure of ThioLox - Thiophene A9

GB40390

ThioLox - Thiophene A9

Also known as 2-amino-N-butyl-5-phenylthiophene-3-carboxamide

Inhibitor of 15-lipoxygenase-1 (15-LOX-1) with both anti-inflammatory and neuroprotective properties (IC50 value of 12 µM)· Ex vivo biological evaluation in precision-cut lung slices (PCLS) showed inhibition of pro-inflammatory gene expression and in vitro studies on neuronal HT-22 cells showed a strong protection against glutamate toxicity for this 15-LOX-1 inhibitor·*Sold in collaboration with RuG (University of Groningen)

ChemicalCAS1202193-89-2MW274.38FormulaC15H18N2OS
CAS number
1202193-89-2
Molecular weight
274.38
Formula
C15H18N2OS
Solubility
DMSO ： 100 mg/mL (364·46 mM; ultrasonic and warming and heat to 60°C)
InChIKey
QWWMJRJCSZMXHZ-UHFFFAOYSA-N
Catalogue number
GB40390
Brand
GLPBIO
Computed properties PubChem CID 53383638 · XLogP 4 · TPSA 83.4 Ų · H-bond donors 2
XLogP
4
TPSA
83.4 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
5
Heavy atoms
19

SMILES CCCCNC(=O)C1=C(SC(=C1)C2=CC=CC=C2)N

Computed descriptors from PubChem (CID 53383638), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.