Loading...
Chemical structure of PVHD121

GB40335

PVHD121

Also known as 1-(4-methoxyphenyl)-1-quinazolin-4-ylethanol

PVHD121 is a potent mitotic inhibitor,an antimitotic agent that selectively disturbs microtubule formation at centrosomes during mitosis· PVHD121 was shown to have strong antiproliferative activity against various tumor-derived cell lines, including A549 (lung), NCI-H460 (lung), HCT116 (colon), MCF7 (breast), PC3 (prostate), and HeLa (cervical) cells with IC50 values from 0·1 to 0·3 μM· Potential tool for studying the molecular biology of mitosis

ChemicalCAS187336-16-9MW280.32FormulaC17H16N2O2
CAS number
187336-16-9
Molecular weight
280.32
Formula
C17H16N2O2
InChIKey
WGDUWVWCDNCAOT-UHFFFAOYSA-N
Catalogue number
GB40335
Brand
GLPBIO
Computed properties PubChem CID 10826594 · XLogP 2.5 · TPSA 55.2 Ų · H-bond donors 1
XLogP
2.5
TPSA
55.2 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
21

SMILES CC(C1=CC=C(C=C1)OC)(C2=NC=NC3=CC=CC=C32)O

Computed descriptors from PubChem (CID 10826594), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.