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Chemical structure of PU-H71 trihydrochloride

GB40334

PU-H71 trihydrochloride

Also known as 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine;trihydrochloride

Potent inhibitor of heat shock protein 90 (Hsp90) with IC50 of 51 nM; inhibits cell growth in a range of breast cancer cell lines; inhibit cell proliferation and induce apoptosis in triple-negative breast cancer (TNBC) cells·Note: On the developers request, this product is not for sale for our customers in the United States

ChemicalCAS2108826-10-2MW621.75FormulaC18H21IN6O2S·3HCl
CAS number
2108826-10-2
Molecular weight
621.75
Formula
C18H21IN6O2S·3HCl
InChIKey
KMHRRRIFDIMTLR-UHFFFAOYSA-N
Catalogue number
GB40334
Brand
GLPBIO
Computed properties PubChem CID 91826484 · TPSA 125 Ų · H-bond donors 5 · H-bond acceptors 8
TPSA
125 Ų
H-bond donors
5
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
31

SMILES CC(C)NCCCN1C2=NC=NC(=C2N=C1SC3=C(C=C4C(=C3)OCO4)I)N.Cl.Cl.Cl

Computed descriptors from PubChem (CID 91826484), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.