GB40315
PDE5 inhibitor 42
Also known as 1-[1-(2-ethoxyethyl)-3-ethyl-7-[(4-methyl-2-pyridinyl)amino]pyrazolo[4,5-d]pyrimidin-5-yl]piperidine-4-carboxylic acid
Potent and selective phosphodiesterase type 5 (PDE5) inhibitor (IC50: 0·04 nM); PDE6/PDE5 and PDE11/PDE5 ratios to be 100x and 530x respectively; a second generation PDE5 inhibitor under investigation
ChemicalCAS936449-28-4MW453.54FormulaC23H31N7O3
- CAS number
- 936449-28-4
- Molecular weight
- 453.54
- Formula
- C23H31N7O3
- InChIKey
- IQZQWPRZFLHJFI-UHFFFAOYSA-N
- Catalogue number
- GB40315
- Brand
- GLPBIO
Computed properties PubChem CID 16066664 · XLogP 2.9 · TPSA 118 Ų · H-bond donors 2
- XLogP
- 2.9
- TPSA
- 118 Ų
- H-bond donors
- 2
- H-bond acceptors
- 9
- Rotatable bonds
- 9
- Heavy atoms
- 33
SMILES CCC1=NN(C2=C1N=C(N=C2NC3=NC=CC(=C3)C)N4CCC(CC4)C(=O)O)CCOCC
Computed descriptors from PubChem (CID 16066664), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il