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Chemical structure of Org OD 02-0 - 19-CH2P4

GB40308

Org OD 02-0 - 19-CH2P4

Also known as (8S,9S,10S,13S,14S,17S)-17-acetyl-10-ethenyl-13-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Selective agonist of membrane progesterone receptor (mPR; IC50 value 33·9 nM)· Org OD 02-0 mimics the protective effects of progestin hormones on serum starvation-induced cell death and apoptosis in both granulosa and breast cancer cells without altering caspase 3 activity· Org OD 02-0 significantly increased mitochondrial membrane potential (MMP) in serum starved MB468 cells

ChemicalCAS13258-85-0MW326.47FormulaC22H30O2
CAS number
13258-85-0
Molecular weight
326.47
Formula
C22H30O2
InChIKey
VFNRBPBEOXXVPX-GCOBIYGJSA-N
Catalogue number
GB40308
Brand
GLPBIO
Computed properties PubChem CID 22212907 · XLogP 4.1 · TPSA 34.1 Ų · H-bond donors 0
XLogP
4.1
TPSA
34.1 Ų
H-bond donors
0
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
24

SMILES CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C=C)C

Computed descriptors from PubChem (CID 22212907), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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