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Chemical structure of Lorcainide HCl

GB40264

Lorcainide HCl

Also known as N-(4-chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-1-ium-4-yl)acetamide chloride

Lorcainide hydrochloride (58934-46-6) is a voltage-gated Na channel blocker· Protects murine cultured cortical neurons from injury induced by oxygen-glucose deprivation· Acts at the ouabain binding site of guinea pig cardiac Na/K ATPase and inhibits the enzyme (IC50 = 34 μM)

ChemicalCAS58934-46-6MW407.38FormulaC22H27ClN2O ? HCl
CAS number
58934-46-6
Molecular weight
407.38
Formula
C22H27ClN2O ? HCl
InChIKey
FSFSWNBDCJVFGI-UHFFFAOYSA-N
Catalogue number
GB40264
Brand
GLPBIO
Computed properties PubChem CID 42883 · TPSA 24.8 Ų · H-bond donors 1 · H-bond acceptors 2
TPSA
24.8 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
5
Heavy atoms
27

SMILES CC(C)[NH+]1CCC(CC1)N(C2=CC=C(C=C2)Cl)C(=O)CC3=CC=CC=C3.[Cl-]

Computed descriptors from PubChem (CID 42883), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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