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Chemical structure of DG2 - S6K1 Inhibitor DG2

GB40176

DG2 - S6K1 Inhibitor DG2

Also known as 3-bromo-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2H-pyrazolo[3,4-d]pyrimidine

Potent and selective inhibitor of p70 ribosomal S6 kinase 1 (S6K1) (IC50: 9·1 nM for S6K1); no Akt activity (IC50: 22000 nM); ATP-competitive and cell-permeable

ChemicalCAS871340-88-4MW389.25FormulaC16H17BrN6O
CAS number
871340-88-4
Molecular weight
389.25
Formula
C16H17BrN6O
InChIKey
CQXAPCMYRSTDGK-UHFFFAOYSA-N
Catalogue number
GB40176
Brand
GLPBIO
Computed properties PubChem CID 25243801 · XLogP 3.2 · TPSA 70.2 Ų · H-bond donors 1
XLogP
3.2
TPSA
70.2 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
24

SMILES COC1=CC=CC=C1N2CCN(CC2)C3=NC=NC4=NNC(=C43)Br

Computed descriptors from PubChem (CID 25243801), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.