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Chemical structure of AG 1478 (Base)

GB40094

AG 1478 (Base)

Also known as N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine

AG-1478 (175478-82-2; base) is a potent and selective inhibitor of the EGFR kinase (IC50 = 3 nM)· Inhibits proliferation of a variety human cancer cell lines· AG-1478 reduces pulmonary fibrosis in a rat model· Cell permeable

ChemicalCAS175178-82-2MW315.76FormulaC16H14ClN3O2
CAS number
175178-82-2
Molecular weight
315.76
Formula
C16H14ClN3O2
InChIKey
GFNNBHLJANVSQV-UHFFFAOYSA-N
Catalogue number
GB40094
Brand
GLPBIO
Computed properties PubChem CID 2051 · XLogP 4 · TPSA 56.3 Ų · H-bond donors 1
XLogP
4
TPSA
56.3 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
22

SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC

Computed descriptors from PubChem (CID 2051), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.