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Chemical structure of Quizartinib Dihydrochloride

GB40091

Quizartinib Dihydrochloride

Also listed as AC 220 dihydrochloride - Quizartinib dihydrochloride

A uniquely potent, selective and efficacious inhibitor of FMS-Like Tyrosine kinase-3 (FLT3) for the treatment of AML; Second-generation FLT3 inhibitor that is highly potent with low nanomolar potency both in vitro and in cellular assays, and has a highly focused and selective interaction pattern across the human protein kinome

ChemicalCAS1132827-21-4MW633.59FormulaC29H32N6O4S·2HCl
CAS number
1132827-21-4
Molecular weight
633.59
Formula
C29H32N6O4S·2HCl
InChIKey
DHYPGRVMIOATAE-UHFFFAOYSA-N
Catalogue number
GB40091
Brand
GLPBIO
Computed properties PubChem CID 25184035 · TPSA 134 Ų · H-bond donors 4 · H-bond acceptors 8
TPSA
134 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
42

SMILES CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3.Cl.Cl

Computed descriptors from PubChem (CID 25184035), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.