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Chemical structure of Prion Protein (106-126) (human) (scrambled)

GA24156

Prion Protein (106-126) (human) (scrambled)

Also known as (2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S,3R)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]acetyl]amino]propanoyl]amino]hexanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]acetyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]acetyl]amino]propanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]propanoyl]amino]propanoyl]amino]propanoic acid

The 21-peptide NGAKALMGGHGATKVMVGAAA, a scrambled sequence of the human prion protein (106-126), is an important control in the study of the biological activity of prion protein peptides

ChemicalCAS150469-23-1MW1912.27
CAS number
150469-23-1
Molecular weight
1912.27
Formula
InChIKey
NTFZQRPSWWDRPI-MBNDGZRNSA-N
Catalogue number
GA24156
Brand
GLPBIO
Computed properties PubChem CID 102601675 · XLogP -8.4 · TPSA 840 Ų · H-bond donors 27
XLogP
-8.4
TPSA
840 Ų
H-bond donors
27
H-bond acceptors
30
Rotatable bonds
64
Heavy atoms
132

SMILES C[C@H]([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC1=CNC=N1)NC(=O)CNC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(=O)N)N)O

Computed descriptors from PubChem (CID 102601675), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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