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Chemical structure of Z-Leu-Arg-Gly-Gly-AMC

GA23848

Z-Leu-Arg-Gly-Gly-AMC

Also known as benzyl N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[2-[[2-[(4-methyl-2-oxochromen-7-yl)amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate

Z-LRGG-AMC is a fluorogenic substrate for isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolases (UCHs) based on the C-termini of ubiquitin with a kcat/Km value of 18 M?¹s?¹· Together with our product I-1690 it forms the basis of continuous assays for precise mechanistic studies or microtiter plate assays for high-throughput inhibitor screening·LRGG is the preferred substrate sequence of the human deSUMOylating enzymes SENP6 and 7·Stock solutions of Boc-LRGG-AMC are best prepared in DMSO

ChemicalCAS167698-68-2MW692.77FormulaC34H44N8O8
CAS number
167698-68-2
Molecular weight
692.77
Formula
C34H44N8O8
Solubility
Soluble in DMSO
InChIKey
UJBADKZGUTUILD-UIOOFZCWSA-N
Catalogue number
GA23848
Brand
GLPBIO
Computed properties PubChem CID 99647803 · XLogP 1.2 · TPSA 245 Ų · H-bond donors 7
XLogP
1.2
TPSA
245 Ų
H-bond donors
7
H-bond acceptors
9
Rotatable bonds
18
Heavy atoms
50

SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)CNC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)OCC3=CC=CC=C3

Computed descriptors from PubChem (CID 99647803), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.