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Chemical structure of Tyrosinase (206-214) (human)

GA23655

Tyrosinase (206-214) (human)

Also known as (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid

AFLPWHRLF is a tyrosinase epitope recognized by HLA-A24 restricted, tumor-infiltrating lymphocytes (TIL)· Therefore it represents a reagent that may be used to generate melanoma-specific T cells for adoptive immunotherapy, as well as in peptide vaccines for HLA-A24+ melanoma patients

ChemicalCAS166188-11-0MW1186.43FormulaC61H83N15O10
CAS number
166188-11-0
Molecular weight
1186.43
Formula
C61H83N15O10
Solubility
DMSO ： 125 mg/mL (105·36 mM; Need ultrasonic)
InChIKey
ZDTHINDBILABAB-WDGXTDPFSA-N
Catalogue number
GA23655
Brand
GLPBIO
Computed properties PubChem CID 9941717 · XLogP 1.4 · TPSA 396 Ų · H-bond donors 13
XLogP
1.4
TPSA
396 Ų
H-bond donors
13
H-bond acceptors
13
Rotatable bonds
32
Heavy atoms
86

SMILES C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CC5=CN=CN5)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)O)N

Computed descriptors from PubChem (CID 9941717), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.