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Chemical structure of Suc-Ala-Phe-Pro-Phe-pNA

GA23550

Suc-Ala-Phe-Pro-Phe-pNA

Also known as 4-[[(2S)-1-[[(2S)-1-(4-nitro-N-[(2S)-1-oxo-3-phenyl-1-[[(2S)-pyrrolidine-2-carbonyl]amino]propan-2-yl]anilino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid

Substrate for FK-506 binding proteins (FKBPs, also called macrophilins) and cyclophilins, which belong to the group of peptidyl prolyl cis-trans isomerases (PPIases)· Suc-AFPF-pNA has been used for an uncoupled protease-free assay of PPIase activity

ChemicalCAS128802-73-3MW700.75FormulaC36H40N6O9
CAS number
128802-73-3
Molecular weight
700.75
Formula
C36H40N6O9
Solubility
Soluble in DMSO
InChIKey
AXCXJCIVUCYJKW-SUFMYBPMSA-N
Catalogue number
GA23550
Brand
GLPBIO
Computed properties PubChem CID 5492460 · XLogP 0.6 · TPSA 220 Ų · H-bond donors 5
XLogP
0.6
TPSA
220 Ų
H-bond donors
5
H-bond acceptors
10
Rotatable bonds
15
Heavy atoms
51

SMILES C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N(C2=CC=C(C=C2)[N+](=O)[O-])[C@@H](CC3=CC=CC=C3)C(=O)NC(=O)[C@@H]4CCCN4)NC(=O)CCC(=O)O

Computed descriptors from PubChem (CID 5492460), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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