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Chemical structure of Pyr-Trp-Gly-NH₂

GA23432

Pyr-Trp-Gly-NH₂

Also known as (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

The tripeptide pEWG-amide found in plasma stimulates the uptake of serotonin into platelets· Increased amounts of pEWG-amide can be detected in the urine of autistic children· The urinary peptide, which is generated from the CNS glycoprotein reelin, has also been associated with depression and anxiety disorders

ChemicalCAS239134-47-5MW371.4FormulaC18H21N5O4
CAS number
239134-47-5
Molecular weight
371.4
Formula
C18H21N5O4
Solubility
Soluble in DMSO
InChIKey
JOSHHTSHCICAQU-KBPBESRZSA-N
Catalogue number
GA23432
Brand
GLPBIO
Computed properties PubChem CID 7408722 · XLogP -1 · TPSA 146 Ų · H-bond donors 5
XLogP
-1
TPSA
146 Ų
H-bond donors
5
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
27

SMILES C1CC(=O)N[C@@H]1C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)NCC(=O)N

Computed descriptors from PubChem (CID 7408722), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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