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Chemical structure of T140 peptide

GA23374

T140 peptide

Also listed as Polyphemusin II-Derived Peptide

Showed the highest inhibitory activity against the T cell line-tropic HIV-1 infection through its specific binding to a chemokine receptor CXCR4 (IC?? = 0·18 ± 0·041 nM) and the strongest inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody to CXCR4 (IC?? = 2·3 ± 0·20 nM)

ChemicalCAS229030-20-0MW2037.45FormulaC90H141N33O18S2
CAS number
229030-20-0
Molecular weight
2037.45
Formula
C90H141N33O18S2
Solubility
Soluble in DMSO
InChIKey
IMOHHNXUCDZLKM-ADZSTZGASA-N
Catalogue number
GA23374
Brand
GLPBIO
Computed properties PubChem CID 16130395 · XLogP -6.4 · TPSA 941 Ų · H-bond donors 35
XLogP
-6.4
TPSA
941 Ų
H-bond donors
35
H-bond acceptors
28
Rotatable bonds
52
Heavy atoms
143

SMILES C1C[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N2C1)CCCCN)CCCCN)CCCNC(=N)N)CC3=CC=C(C=C3)O)NC(=O)[C@H](CC4=CC5=CC=CC=C5C=C4)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)CCCNC(=O)N)CCCNC(=N)N)CC6=CC=C(C=C6)O

Computed descriptors from PubChem (CID 16130395), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.