GA23210
Myristoyl-(Lys¹²,²⁷,²⁸)-VIP-Gly-Gly-Thr (free acid)
PG 99-465 is a high affinity, selective VPAC2 receptor antagonist· It exhibited a 100-fold preference for the VPAC2 over the VPAC1 receptor· The compound showed partial agonistic activity on the VPAC1 receptor and was inactive on the VPAC2 receptor transfected in CHO cells, as well as on naturally expressed human VPAC2 receptors in the SUP T1 cell line· Dickson et al· observed an agonistic effect of PG99-465 on the human VPAC1 and PAC1 receptors· When applied singly, PG99-465 increased [cAMP](i) at all three hVPAC/PAC receptor subtypes
ChemicalMW3753.47FormulaC171H283N45O47S
- CAS number
- —
- Molecular weight
- 3753.47
- Formula
- C171H283N45O47S
- Solubility
- Soluble in DMSO
- Catalogue number
- GA23210
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il