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Chemical structure of Leptin (116-130) (human)

GA23132

Leptin (116-130) (human)

Also known as (4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-sulfanylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3R)-1-[[(2S)-1-[[(2S)-3-carboxy-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Fragment of human leptin, an adipose tissue-derived protein encoded by the obese gene· Leptin has been implicated in the control of food intake, energy expenditure and reproduction· Additional roles in the regulation of immunity, inflammation, and hematopoiesis have been proposed

ChemicalCAS2243207-12-5MW1615.76FormulaC70H106N18O24S
CAS number
2243207-12-5
Molecular weight
1615.76
Formula
C70H106N18O24S
Solubility
Soluble in DMSO
InChIKey
YUWVNLMTEGHKIG-OPDXBULCSA-N
Catalogue number
GA23132
Brand
GLPBIO
Computed properties PubChem CID 101399033 · XLogP -6.4 · TPSA 663 Ų · H-bond donors 24
XLogP
-6.4
TPSA
663 Ų
H-bond donors
24
H-bond acceptors
27
Rotatable bonds
48
Heavy atoms
113

SMILES C[C@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC4=CN=CN4)NC(=O)[C@H](CS)NC(=O)[C@H](CO)N)O

Computed descriptors from PubChem (CID 101399033), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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