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Chemical structure of IGF-I Analog

GA23100

IGF-I Analog

Also known as (2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-(7-hydroxy-3,8-dithiatricyclo[5.1.0.02,4]oct-5-en-4-yl)propanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-3-oxopropanoyl]amino]propanoic acid

The IGF-I peptide analog JB-1 was able to inhibit the autophosphorylation of the IGF-I receptor by IGF-I as well as the growth of several different cell types, including prostate carcinoma cells and SV40-transformed cells· IGF1 analogs as JB-1 might be useful in treating abnormal cell growth

ChemicalCAS147819-32-7MW1249.52FormulaC55H88N14O15S2
CAS number
147819-32-7
Molecular weight
1249.52
Formula
C55H88N14O15S2
Solubility
Soluble in DMSO
InChIKey
CWDBKYUARDUIEM-KTQAENQISA-N
Catalogue number
GA23100
Brand
GLPBIO
Computed properties PubChem CID 5491959 · XLogP -4.7 · TPSA 506 Ų · H-bond donors 14
XLogP
-4.7
TPSA
506 Ų
H-bond donors
14
H-bond acceptors
20
Rotatable bonds
34
Heavy atoms
86

SMILES C[C@@H](C(=O)N[C@@H](CC12C=CC3(C(C1S2)S3)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N5CCC[C@H]5C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C=O)C(=O)N[C@@H](C)C(=O)O)N

Computed descriptors from PubChem (CID 5491959), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.