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Chemical structure of H-Lys-Arg-Thr-Leu-Arg-OH

GA22687

H-Lys-Arg-Thr-Leu-Arg-OH

Also known as (2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid

The pentapeptide KRTLR, which is based on the Thr-654 phosphorylation site in the EGF receptor, is a weak substrate of protein kinase C (Km app = 300 ± 40 µM)

ChemicalCAS121145-48-0MW672.83FormulaC28H56N12O7
CAS number
121145-48-0
Molecular weight
672.83
Formula
C28H56N12O7
Solubility
Soluble in DMSO
InChIKey
LGIVVZKNEWRIPR-CEGNMAFCSA-N
Catalogue number
GA22687
Brand
GLPBIO
Computed properties PubChem CID 99651211 · XLogP -5.9 · TPSA 355 Ų · H-bond donors 12
XLogP
-5.9
TPSA
355 Ų
H-bond donors
12
H-bond acceptors
11
Rotatable bonds
24
Heavy atoms
47

SMILES C[C@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)N)O

Computed descriptors from PubChem (CID 99651211), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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