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Chemical structure of H-Lys(Abz)-Pro-Pro-pNA

GA22663

H-Lys(Abz)-Pro-Pro-pNA

Also known as (2S)-1-[(2S)-1-[(2S)-2-amino-6-[(2-aminobenzoyl)amino]hexanoyl]pyrrolidine-2-carbonyl]-N-(4-nitrophenyl)pyrrolidine-2-carboxamide

Internally quenched fluorogenic (FRET) substrate which allows aminopeptidase P (APP) activity determination by a continuous fluorescent assay (kcat/Km = 29'000 M?¹s?¹ for E·coli APP and kcat/Km = 1'142'000 M?¹s?¹ for rat APP)

ChemicalCAS219138-18-8MW579.66FormulaC29H37N7O6
CAS number
219138-18-8
Molecular weight
579.66
Formula
C29H37N7O6
Solubility
Soluble in DMSO
InChIKey
PYDKOXBAMHOEAF-SDHOMARFSA-N
Catalogue number
GA22663
Brand
GLPBIO
Computed properties PubChem CID 95566045 · XLogP 2.1 · TPSA 197 Ų · H-bond donors 4
XLogP
2.1
TPSA
197 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
42

SMILES C1C[C@H](N(C1)C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCCNC(=O)C3=CC=CC=C3N)N)C(=O)NC4=CC=C(C=C4)[N+](=O)[O-]

Computed descriptors from PubChem (CID 95566045), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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