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Chemical structure of H-Lys(4-nitro-Z)-OH

GA22662

H-Lys(4-nitro-Z)-OH

Also known as (2S)-2-amino-6-[(4-nitrophenyl)methoxycarbonylamino]hexanoic acid

The 4-Nitro-Z (pNZ) group has gained interest as semipermanent Nε protecting group in combination with Fmoc/tBu/Aloc· It can be removed selectively with SnCl?/HCl in DMF·E-2960 is used as inactive control in studies using the DPP IV inhibitors H-Lys(4-nitro-Z)-pyrrolidide, N-1710, and H-Lys(4-nitro-Z)-thiazolidide

ChemicalCAS3557-90-2MW325.32FormulaC14H19N3O6
CAS number
3557-90-2
Molecular weight
325.32
Formula
C14H19N3O6
Solubility
Soluble in DMSO
InChIKey
XMTCOKGMBIHVBJ-LBPRGKRZSA-N
Catalogue number
GA22662
Brand
GLPBIO
Computed properties PubChem CID 11244255 · XLogP -1.3 · TPSA 147 Ų · H-bond donors 3
XLogP
-1.3
TPSA
147 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
9
Heavy atoms
23

SMILES C1=CC(=CC=C1COC(=O)NCCCC[C@@H](C(=O)O)N)[N+](=O)[O-]

Computed descriptors from PubChem (CID 11244255), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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