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Chemical structure of H-Leu-Ser-Lys-Leu-OH

GA22646

H-Leu-Ser-Lys-Leu-OH

Also known as (2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-4-methylpentanoic acid

The tetrapeptide LSKL prevents hepatic fibrosis in vivo via blocking TGFβ1 activation· LSAL (H-2144) has been used as inactive control

ChemicalCAS162559-45-7MW459.59FormulaC21H41N5O6
CAS number
162559-45-7
Molecular weight
459.59
Formula
C21H41N5O6
Solubility
Soluble in DMSO
InChIKey
KEJKLBKXNJSXOW-QAETUUGQSA-N
Catalogue number
GA22646
Brand
GLPBIO
Computed properties PubChem CID 9933915 · XLogP -2.8 · TPSA 197 Ų · H-bond donors 7
XLogP
-2.8
TPSA
197 Ų
H-bond donors
7
H-bond acceptors
8
Rotatable bonds
16
Heavy atoms
32

SMILES CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O)N

Computed descriptors from PubChem (CID 9933915), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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