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Chemical structure of H-Leu-Ile-OH

GA22627

H-Leu-Ile-OH

Also known as (2S,3S)-2-[[(2S)-2-azaniumyl-4-methylpentanoyl]amino]-3-methylpentanoate

According to Nitta et al· H-Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor synthesis· Alkam et al· observed that dietary supplementation with the hydrophobic dipeptide prevents the impairment of memory induced by amyloid β in mice via restraining the hyperphosphorylation of extracellular signal-regulated kinase·Leu-Ile forms nanotubes in the presence of D-leucine

ChemicalCAS36077-41-5MW244.33FormulaC12H24N2O3
CAS number
36077-41-5
Molecular weight
244.33
Formula
C12H24N2O3
Solubility
Soluble in DMSO
InChIKey
AZLASBBHHSLQDB-GUBZILKMSA-N
Catalogue number
GA22627
Brand
GLPBIO
Computed properties PubChem CID 7010533 · XLogP -1 · TPSA 96.9 Ų · H-bond donors 2
XLogP
-1
TPSA
96.9 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
17

SMILES CC[C@H](C)[C@@H](C(=O)[O-])NC(=O)[C@H](CC(C)C)[NH3+]

Computed descriptors from PubChem (CID 7010533), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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