Loading...
Chemical structure of HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22)

GA22603

HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22)

Also known as (2S)-6-amino-2-[[2-[[(2S,3S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S,3S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]hexanoic acid

P18IIIB, derived from the V3 loop of HIV-1 IIIB gp120 efficiently blocked HIV-1 IIIB infection of several T-cell lines and of normal human T cells· RIQRGPGRAFVTIGK also blocked syncytium formation in human cells· Moreover, P18IIIB was capable of inducing HIV-1 specific cytotoxic T lymphocyte responses that could effectively kill virus-infected cells and could thus find several therapeutic applications

ChemicalCAS114991-28-5MW1655.97FormulaC73H126N26O18
CAS number
114991-28-5
Molecular weight
1655.97
Formula
C73H126N26O18
Solubility
Soluble in DMSO
InChIKey
SMHASQROABALLM-ROQHZCFESA-N
Catalogue number
GA22603
Brand
GLPBIO
Computed properties PubChem CID 25078052 · XLogP -7.9 · TPSA 744 Ų · H-bond donors 24
XLogP
-7.9
TPSA
744 Ų
H-bond donors
24
H-bond acceptors
23
Rotatable bonds
55
Heavy atoms
117

SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)N

Computed descriptors from PubChem (CID 25078052), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.