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Chemical structure of HIV Protease Substrate IV

GA22601

HIV Protease Substrate IV

Also known as (4S)-5-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-5-oxopentanoic acid

Sensitive chromogenic substrate for both the HIV-1 and HIV-2 proteases· Kinetic parameters for the cleavage of H-1048: vmax 0·88 µM sec?¹ µg?¹, Km 15 µM, kcat 4·9 sec?¹

ChemicalCAS128340-47-6MW1090.29FormulaC49H83N15O13
CAS number
128340-47-6
Molecular weight
1090.29
Formula
C49H83N15O13
Solubility
Soluble in DMSO
InChIKey
MJGGTDHEIUOPEB-WBMHOGBOSA-N
Catalogue number
GA22601
Brand
GLPBIO
Computed properties PubChem CID 15954055 · XLogP -2.4 · TPSA 475 Ų · H-bond donors 14
XLogP
-2.4
TPSA
475 Ų
H-bond donors
14
H-bond acceptors
16
Rotatable bonds
37
Heavy atoms
77

SMILES CCCC[C@@H](C(=O)N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)[C@H](CCCC)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)N

Computed descriptors from PubChem (CID 15954055), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.