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Chemical structure of H-His-Trp-OH

GA22547

H-His-Trp-OH

Also known as (2S)-2-[[(2S)-2-azaniumyl-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoate

The dipeptide Trp-His shows vasodilatatory activity· Matsui et al· demonstrated that WH inhibits the development of atherosclerosis onsets in ApoE -/- mice

ChemicalCAS23403-90-9MW341.37FormulaC17H19N5O3
CAS number
23403-90-9
Molecular weight
341.37
Formula
C17H19N5O3
Solubility
Soluble in DMSO
InChIKey
FBTYOQIYBULKEH-ZFWWWQNUSA-N
Catalogue number
GA22547
Brand
GLPBIO
Computed properties PubChem CID 7009649 · XLogP -1.8 · TPSA 141 Ų · H-bond donors 4
XLogP
-1.8
TPSA
141 Ų
H-bond donors
4
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
25

SMILES C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)[O-])NC(=O)[C@H](CC3=CN=CN3)[NH3+]

Computed descriptors from PubChem (CID 7009649), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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