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Chemical structure of H-His-Leu-OH

GA22538

H-His-Leu-OH

Also known as (2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoic acid

His-Leu, C-terminal dipeptide of angiotensin I is split off by action of angiotensin-converting enzyme (ACE) yielding angiotensin II· See also M-1305 and M-1485·The complex generated from Cu(II), His-Leu and ethylene diamine (or His) hydrolytically cleaves the phosphodiester backbone of DNA

ChemicalCAS7763-65-7MW268.32FormulaC12H20N4O3
CAS number
7763-65-7
Molecular weight
268.32
Formula
C12H20N4O3
Solubility
Soluble in DMSO
InChIKey
MMFKFJORZBJVNF-UWVGGRQHSA-N
Catalogue number
GA22538
Brand
GLPBIO
Computed properties PubChem CID 189008 · XLogP -2.2 · TPSA 121 Ų · H-bond donors 4
XLogP
-2.2
TPSA
121 Ų
H-bond donors
4
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
19

SMILES CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CN=CN1)N

Computed descriptors from PubChem (CID 189008), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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