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Chemical structure of H-Gly-Arg-AMC

GA22410

H-Gly-Arg-AMC

Also known as (2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)-N-(4-methyl-2-oxochromen-7-yl)pentanamide

H-Gly-Arg-AMC is a fluorogenic substrate for cathepsin C, with maximum excitation/emission wavelengths of 340-360/440-460nm

ChemicalCAS65147-19-5MW388.43FormulaC18H24N6O4
CAS number
65147-19-5
Molecular weight
388.43
Formula
C18H24N6O4
Solubility
DMSO ： 125 mg/mL (321·82 mM; Need ultrasonic); H2O ： ≥ 50 mg/mL (128·73 mM)
InChIKey
JNTASUHAFOHMQK-ZDUSSCGKSA-N
Catalogue number
GA22410
Brand
GLPBIO
Computed properties PubChem CID 493582 · XLogP -1.4 · TPSA 175 Ų · H-bond donors 5
XLogP
-1.4
TPSA
175 Ų
H-bond donors
5
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
28

SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CN

Computed descriptors from PubChem (CID 493582), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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