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Chemical structure of H-Glu(Tyr-OH)-OH

GA22366

H-Glu(Tyr-OH)-OH

Also known as (2S)-2-amino-5-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid

H-Glu(Tyr-OH)-OH is a dipeptide composed of glutamic acid (Glu) and tyrosine (Tyr)· Its chemical name is L-glutamyl-L-tyrosine, with the molecular formula C₁₄H₁₈N₂O₆ and a molecular weight of approximately 310·3· H-Glu(Tyr-OH)-OH is a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC₅₀ = 6·77mM) and may have potential for the treatment of type II diabetes

ChemicalCAS7432-23-7MW310.31FormulaC14H18N2O6
CAS number
7432-23-7
Molecular weight
310.31
Formula
C14H18N2O6
Solubility
Soluble in DMSO
InChIKey
VVLXCWVSSLFQDS-QWRGUYRKSA-N
Catalogue number
GA22366
Brand
GLPBIO
Computed properties PubChem CID 94340 · XLogP -3.8 · TPSA 150 Ų · H-bond donors 5
XLogP
-3.8
TPSA
150 Ų
H-bond donors
5
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
22

SMILES C1=CC(=CC=C1C[C@@H](C(=O)O)NC(=O)CC[C@@H](C(=O)O)N)O

Computed descriptors from PubChem (CID 94340), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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