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Chemical structure of H-D-Phe-Phe-Arg-chloromethylketone

GA22295

H-D-Phe-Phe-Arg-chloromethylketone

Also known as (2R)-2-amino-N-[(2S)-2-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-3-phenylpropanoyl]-3-phenylpropanamide

Kallikrein inhibitor which is even effective in preventing apolipoprotein B-100 proteolysis in dextran sulfate (DS)-precipitated human plasma low density lipoproteins (LDL)·D-FFR-CMK also inhibits gingipain R

ChemicalCAS74392-49-7MW501.03FormulaC25H33ClN6O3
CAS number
74392-49-7
Molecular weight
501.03
Formula
C25H33ClN6O3
Solubility
Soluble in DMSO
InChIKey
UFXAQJOOAQICNE-HKBOAZHASA-N
Catalogue number
GA22295
Brand
GLPBIO
Computed properties PubChem CID 126484 · XLogP 1.6 · TPSA 166 Ų · H-bond donors 5
XLogP
1.6
TPSA
166 Ų
H-bond donors
5
H-bond acceptors
6
Rotatable bonds
14
Heavy atoms
35

SMILES C1=CC=C(C=C1)C[C@H](C(=O)NC(=O)[C@H](CC2=CC=CC=C2)N[C@@H](CCCN=C(N)N)C(=O)CCl)N

Computed descriptors from PubChem (CID 126484), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.