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Chemical structure of H-Arg-Gly-Tyr-Ala-Leu-Gly-OH

GA22082

H-Arg-Gly-Tyr-Ala-Leu-Gly-OH

Also known as 2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]acetic acid

The hexapeptide RGYALG, which is an analog of a phosphorylation site in hen egg white lysozyme, acts as a competitive inhibitor of phosphorylation by cAMP-dependent protein kinase

ChemicalCAS59587-24-5MW635.72FormulaC28H45N9O8
CAS number
59587-24-5
Molecular weight
635.72
Formula
C28H45N9O8
Solubility
Soluble in DMSO
InChIKey
RPAKYHDUWYQJQN-FIRPJDEBSA-N
Catalogue number
GA22082
Brand
GLPBIO
Computed properties PubChem CID 15020119 · XLogP -4.7 · TPSA 293 Ų · H-bond donors 10
XLogP
-4.7
TPSA
293 Ų
H-bond donors
10
H-bond acceptors
10
Rotatable bonds
19
Heavy atoms
45

SMILES C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)N

Computed descriptors from PubChem (CID 15020119), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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