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Chemical structure of Guanylin (mouse, rat)

GA21930

Guanylin (mouse, rat)

Also known as (1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-25-[[(2S,3R)-2-[[(2S)-4-amino-4-oxo-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-3-hydroxybutanoyl]amino]-19-[(2S)-butan-2-yl]-22-(2-carboxyethyl)-32-[(1R)-1-hydroxyethyl]-10-[(4-hydroxyphenyl)methyl]-4,7,13-trimethyl-3,6,9,12,15,18,21,24,30,33,36-undecaoxo-27,28,40,41-tetrathia-2,5,8,11,14,17,20,23,31,34,37-undecazabicyclo[14.13.13]dotetracontane-38-carboxylic acid

Guanylin activates the guanylate cyclase in the intestine to stimulate the production of cGMP, which in turn causes a secretory diarrhoea· Therefore, this peptide may play a role in regulating fluid and electrolyte absorption in intestines

ChemicalCAS144940-98-7MW1515.73FormulaC60H90N16O22S4
CAS number
144940-98-7
Molecular weight
1515.73
Formula
C60H90N16O22S4
Solubility
Soluble in DMSO
InChIKey
VGFLUTOEMABSGC-RAJPIYRYSA-N
Catalogue number
GA21930
Brand
GLPBIO
Computed properties PubChem CID 90470068 · XLogP -6.5 · TPSA 699 Ų · H-bond donors 21
XLogP
-6.5
TPSA
699 Ų
H-bond donors
21
H-bond acceptors
27
Rotatable bonds
18
Heavy atoms
102

SMILES CC[C@H](C)[C@H]1C(=O)N[C@H]2CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N1)CCC(=O)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@@H]3CCCN3)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)C)CC4=CC=C(C=C4)O)C)C)[C@@H](C)O)C(=O)O

Computed descriptors from PubChem (CID 90470068), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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