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Chemical structure of FSL-1-FLAG

GA21885

FSL-1-FLAG

The lipopeptide FSL-1, synthesized on the basis of the N-terminal structure of a M· salivarium lipoprotein, is capable of inducing the cell surface expression of ICAM-1 in human gingival fibroblasts· It furthermore revealed an activity to induce production of monocyte chemoattractant protein 1, interleukin-6 (IL-6), and IL-8· FSL-1 also activated macrophages to produce tumor necrosis factor alpha· Overall, results by Okusawa and coworkers suggest that the diacylglyceryl and the peptide portions of FSL-1 are indispensable for the expression of biological activities and for the recognition by Toll-like receptors 2 and 6· Furthermore, the same authors conclude that the recognition of FSL-1 by Toll-like receptors 2 and 6 apparently is hydrophobic

ChemicalMW2661.15FormulaC125H198N24O37S
CAS number
—
Molecular weight
2661.15
Formula
C125H198N24O37S
Solubility
Soluble in DMSO
Catalogue number
GA21885
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.