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Chemical structure of Fmoc-γ-azido-Abu-OH

GA21869

Fmoc-γ-azido-Abu-OH

Also known as (2S)-4-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid

Protected derivative of L-azidohomoalanine (Aha), a Met isostere·This building block for 'click chemistry' additionally creates a specific cleavage site in peptides, Aha-containing sequences can be cleaved under mild conditions in the presence of phosphines or dithiols via formation of homoserine lactone

ChemicalCAS942518-20-9MW366.38FormulaC19H18N4O4
CAS number
942518-20-9
Molecular weight
366.38
Formula
C19H18N4O4
Solubility
Soluble in DMSO
InChIKey
CLEZARXVEABQBI-KRWDZBQOSA-N
Catalogue number
GA21869
Brand
GLPBIO
Computed properties PubChem CID 25146060 · XLogP 4 · TPSA 90 Ų · H-bond donors 2
XLogP
4
TPSA
90 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
27

SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CCN=[N+]=[N-])C(=O)O

Computed descriptors from PubChem (CID 25146060), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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