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Chemical structure of Fmoc-L-azetidine-2-carboxylic acid

GA21705

Fmoc-L-azetidine-2-carboxylic acid

Also known as (2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)azetidine-2-carboxylic acid

A suitable derivative for incorporating this strained proline analog in peptides to modify their conformation· Its influence on the stability of the collagen helix has been studied by Zagari et al· Fmoc-Aze-OH was employed in the solid-phase synthesis of potent cyclic GnRH analogs

ChemicalCAS136552-06-2MW323.35FormulaC19H17NO4
CAS number
136552-06-2
Molecular weight
323.35
Formula
C19H17NO4
Solubility
Soluble in DMSO
InChIKey
BXRZCDISGRVJCA-KRWDZBQOSA-N
Catalogue number
GA21705
Brand
GLPBIO
Computed properties PubChem CID 2734468 · XLogP 3 · TPSA 66.8 Ų · H-bond donors 1
XLogP
3
TPSA
66.8 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
24

SMILES C1CN([C@@H]1C(=O)O)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Computed descriptors from PubChem (CID 2734468), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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