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Chemical structure of Fmoc-Cys(SASRIN™ resin)-OH (200-400 mesh, 0·3-0·6 mmol/g)

GA21562

Fmoc-Cys(SASRIN™ resin)-OH (200-400 mesh, 0·3-0·6 mmol/g)

This resin has been developed to allow C-terminal modification of cysteine-containing peptides· Fmoc-protected cysteine is linked to SASRIN™-resin by its thiol moiety, which thus is already protected· After derivatization of the carboxylic acid (and, if desired, standard Fmoc-SPPS) lthe modified cysteine derivative can be cleaved with TFA/water/triisopropylsilane (94:4:2, v/v/v) from the SASRIN™-resin· Extending the peptide chain at the C-terminus can be achieved by activation of the side-chain linked cysteine carboxylic acid and coupling to additional amino acids·Cys linked to a resin by its thiol function was oxidized with MCPBA after esterification and Nα-modification (Yamada et al·)· DBU-induced elimination yielded dehydroalanine derivatives

Chemical
CAS number
Molecular weight
Formula
Solubility
Soluble in DMSO
Catalogue number
GA21562
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.