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Chemical structure of Fmoc-cis-4-fluoro-Pro-OH

GA21548

Fmoc-cis-4-fluoro-Pro-OH

Also known as (2S,4S)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid

Stabilizes the PPII helix in Pro-rich short peptides, though less efficiently than the trans isomer· Oligomers of flp were studied by Horng and Raines

ChemicalCAS203866-19-7MW355.37FormulaC20H18FNO4
CAS number
203866-19-7
Molecular weight
355.37
Formula
C20H18FNO4
Solubility
Soluble in DMSO
InChIKey
CJEQUGHYFSTTQT-SGTLLEGYSA-N
Catalogue number
GA21548
Brand
GLPBIO
Computed properties PubChem CID 2756199 · XLogP 3.4 · TPSA 66.8 Ų · H-bond donors 1
XLogP
3.4
TPSA
66.8 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
26

SMILES C1[C@@H](CN([C@@H]1C(=O)O)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)F

Computed descriptors from PubChem (CID 2756199), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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