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Chemical structure of Fmoc-Asn(Mtt)-OH

GA21528

Fmoc-Asn(Mtt)-OH

Also known as (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[[(4-methylphenyl)-diphenylmethyl]amino]-4-oxobutanoic acid

Mtt carboxamide protection is superior to Trt when synthesizing peptides containing an N-terminal Asn, as the latter is cleaved only sluggishly in this position

ChemicalCAS144317-22-6MW610.71FormulaC39H34N2O5
CAS number
144317-22-6
Molecular weight
610.71
Formula
C39H34N2O5
Solubility
Soluble in DMSO
InChIKey
IIZBWIYTHRCCFO-DHUJRADRSA-N
Catalogue number
GA21528
Brand
GLPBIO
Computed properties PubChem CID 56777273 · XLogP 7 · TPSA 105 Ų · H-bond donors 3
XLogP
7
TPSA
105 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
11
Heavy atoms
46

SMILES CC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)C[C@@H](C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46

Computed descriptors from PubChem (CID 56777273), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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