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Chemical structure of FITC-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH (Contains FITC isomer I)

GA21459

FITC-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH (Contains FITC isomer I)

Also known as (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-yl)carbamothioylamino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-6-(2,4-dinitroanilino)hexanoic acid

FITC-YVADAPK(Dnp) is a specific FRET substrate for the determination of caspase-1 and caspase-1 like enzyme activities· Cleavage of FITC-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay· It is useful both in FACS and fluorescence microscopy experiments· Caspase-3 is only weakly active using this substrate· See also our reference substance M-2280

ChemicalCAS1926163-32-7MW1318.34FormulaC62H67N11O20S
CAS number
1926163-32-7
Molecular weight
1318.34
Formula
C62H67N11O20S
Solubility
Soluble in DMSO
InChIKey
CSHXTBYHFOGNFN-GBZKBENMSA-N
Catalogue number
GA21459
Brand
GLPBIO
Computed properties PubChem CID 131698197 · XLogP 5.7 · TPSA 496 Ų · H-bond donors 13
XLogP
5.7
TPSA
496 Ų
H-bond donors
13
H-bond acceptors
22
Rotatable bonds
25
Heavy atoms
94

SMILES C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-])C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=S)NC4=CC5=C(C=C4)C(=O)OC56C7=C(C=C(C=C7)O)OC8=C6C=CC(=C8)O

Computed descriptors from PubChem (CID 131698197), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.