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Chemical structure of Diphenyldiazomethane resin (200-400 mesh, 0·7-1·3 mmol/g)

GA21381

Diphenyldiazomethane resin (200-400 mesh, 0·7-1·3 mmol/g)

Diphenyldiazomethane was used industrially for producing benzhydryl esters (diphenylmethyl esters) of β-lactam antibiotics· This "polymeric diphenyldiazomethane" readily reacts with carboxylic acids, e·g· Fmoc-amino acids, which need not to be activated· Products can be cleaved from this very acid-sensitive resin derivative with 1-5 % TFA in dichloromethane·Fmoc-α-amino alcohols can be anchored to PDDM in the presence of BF? etherate· As the resulting benzhydryl ethers can be cleaved with 1% TFA/DCM, fully protected peptide alcohols can be obtained

Chemical
CAS number
Molecular weight
Formula
Solubility
Soluble in DMSO
Catalogue number
GA21381
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.