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Chemical structure of Carbamoyl-Asp-OH · magnesium salt/Carbamoyl-Asp-OH · dipotassium salt (1:1)

GA21245

Carbamoyl-Asp-OH · magnesium salt/Carbamoyl-Asp-OH · dipotassium salt (1:1)

Substrate for the determination of E·coli dihydroorotase (EC 3·5·2·3·), which catalyzes the cyclization of carbamoyl-Asp-OH into L-5,6-dihydroorotate· This enzyme being in the biosynthetic pathway of pyrimidine nucleotides, is an important therapeutic target for the design of new antineoplastic agents· Its activity was assayed spectrophotometrically measuring the increase of absorbance at 230 nm (ε??? = 1170 M?¹cm?¹, Km = 0·47 mM, kcat = 143 s?¹)

ChemicalCAS13184-27-5MW450.73FormulaC10H12K2MgN4O10
CAS number
13184-27-5
Molecular weight
450.73
Formula
C10H12K2MgN4O10
Solubility
H2O : 35 mg/mL (198·72 mM; Need ultrasonic)
Catalogue number
GA21245
Brand
GLPBIO

Ordering in Israel

Lead time
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