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Chemical structure of Boc-cis-Hyp-OMe

GA20914

Boc-cis-Hyp-OMe

Also known as 1-O-tert-butyl 2-O-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate

N-Boc-cis-4-hydroxy-L-proline methyl ester is a non-cleavableADC linkerused in the synthesis of antibody-drug conjugates (ADCs)· N-Boc-cis-4-hydroxy-L-proline methyl ester is also a alkyl chain-based PROTAC linkerthat can be used in the synthesis of PROTACs[2

ChemicalCAS102195-79-9MW245.28FormulaC11H19NO5
CAS number
102195-79-9
Molecular weight
245.28
Formula
C11H19NO5
Solubility
Soluble in DMSO
InChIKey
MZMNEDXVUJLQAF-YUMQZZPRSA-N
Catalogue number
GA20914
Brand
GLPBIO
Computed properties PubChem CID 10752873 · XLogP 0.6 · TPSA 76.1 Ų · H-bond donors 1
XLogP
0.6
TPSA
76.1 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
17

SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)OC)O

Computed descriptors from PubChem (CID 10752873), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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