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Chemical structure of Boc-Asp(OBzl)-chloromethylketone

GA20905

Boc-Asp(OBzl)-chloromethylketone

Also known as benzyl (3S)-5-chloro-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxopentanoate

Boc-Asp(OBzl)-CMK penetrates cells and binds covalently to the active site of caspase-1 (ICE)· At a concentration of 2·5 µM, this inhibitor reduces caspase-1-mediated processing of mature interleukin-1β in a monocytic cell line by 85 % without affecting tumor necrosis factor processing

ChemicalCAS172702-58-8MW355.82FormulaC17H22ClNO5
CAS number
172702-58-8
Molecular weight
355.82
Formula
C17H22ClNO5
Solubility
Soluble in DMSO
InChIKey
BKSBJYSNALKVEA-ZDUSSCGKSA-N
Catalogue number
GA20905
Brand
GLPBIO
Computed properties PubChem CID 7020821 · XLogP 2.7 · TPSA 81.7 Ų · H-bond donors 1
XLogP
2.7
TPSA
81.7 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
10
Heavy atoms
24

SMILES CC(C)(C)OC(=O)N[C@@H](CC(=O)OCC1=CC=CC=C1)C(=O)CCl

Computed descriptors from PubChem (CID 7020821), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.