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Chemical structure of Biotin-DEVD-CHO

GA20827

Biotin-DEVD-CHO

Also listed as Biotinyl-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

This biotinylated apopain inhibitor has successfully been used for the affinity purification - on a streptavidin-agarose column - of caspase-3 (apopain), the enzyme that cleaves the poly(ADP-ribose) polymerase (PARP)· Biotinyl-DEVD-CHO showed an inhibitory activity comparable to that of the N-acetylated analog inhibitor (H-2496) (IC?? = 0·2 nM)

ChemicalCAS178603-73-1MW686.74FormulaC28H42N6O12S
CAS number
178603-73-1
Molecular weight
686.74
Formula
C28H42N6O12S
Solubility
Soluble in DMSO
InChIKey
NOYOANDLKBWUGA-AUJWPLEISA-N
Catalogue number
GA20827
Brand
GLPBIO
Computed properties PubChem CID 644346 · XLogP -2 · TPSA 312 Ų · H-bond donors 9
XLogP
-2
TPSA
312 Ų
H-bond donors
9
H-bond acceptors
13
Rotatable bonds
21
Heavy atoms
47

SMILES CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CCCC[C@H]1[C@@H]2[C@H](CS1)NC(=O)N2

Computed descriptors from PubChem (CID 644346), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.