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Chemical structure of Asn-Ala-Intercellular Adhesion Molecule 1 (1-21) (human)

GA20781

Asn-Ala-Intercellular Adhesion Molecule 1 (1-21) (human)

Also known as (2R)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]propanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-sulfanylpropanoic acid

Asn-Ala-ICAM 1 (1-21) inhibits virus replication in HIV-1 infected HTLV-1 transformed cells (MT-2 cells)· The peptide induces up to 70% inhibition of reverse transcriptase activity, up to 60% reduction of soluble virus antigen production, and inhibition of syncytium formation

ChemicalCAS139227-42-2MW2313.72FormulaC99H173N29O32S
CAS number
139227-42-2
Molecular weight
2313.72
Formula
C99H173N29O32S
Solubility
Soluble in DMSO
InChIKey
UGBRDKWUHRXHEN-LLWGBTACSA-N
Catalogue number
GA20781
Brand
GLPBIO
Computed properties PubChem CID 102601651 · XLogP -10.2 · TPSA 982 Ų · H-bond donors 35
XLogP
-10.2
TPSA
982 Ų
H-bond donors
35
H-bond acceptors
36
Rotatable bonds
74
Heavy atoms
161

SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)N)N

Computed descriptors from PubChem (CID 102601651), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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