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Chemical structure of Apelin-36 (1-16) amide (human)

GA20777

Apelin-36 (1-16) amide (human)

Also known as (2S)-2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-1-[2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-oxobutanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-(2-amino-2-oxoethyl)pentanediamide

SCNH2 ("selective apelin-36 cutting and amidation" peptide) is apelin-36-derived secondary bioactive peptide, highly expressed in human tumors and placenta and in mouse embryonic tissues· The peptide amide is mitogenic and chemotactic in normal and malignant cells and augments angiogenesis· SCNH2 is substantially more potent and sensitive than apelin-13 and vascular endothelial growth factor-A

ChemicalCAS1241836-78-1MW1704.91FormulaC74H117N27O20
CAS number
1241836-78-1
Molecular weight
1704.91
Formula
C74H117N27O20
Solubility
Soluble in DMSO
InChIKey
PSBCAWRMSGVLJZ-ZCFGCKJDSA-N
Catalogue number
GA20777
Brand
GLPBIO
Computed properties PubChem CID 131846084 · XLogP -8.4 · TPSA 768 Ų · H-bond donors 25
XLogP
-8.4
TPSA
768 Ų
H-bond donors
25
H-bond acceptors
23
Rotatable bonds
52
Heavy atoms
121

SMILES CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N2CCC[C@H]2C(=O)NCC(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CNC5=CC=CC=C54)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N)N

Computed descriptors from PubChem (CID 131846084), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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