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Chemical structure of Amyloid β-Protein (4-42)

GA20754

Amyloid β-Protein (4-42)

Aβ 4-42 could be one of the earliest and most prominent Aβ species deposited in AD brain· Sequencing of amyloid plaque cores showed that 64% of the isolated Aβ had a phenylalanine at its N-terminus, and indeed, IP/MS experiments identified Aβ 4-42 as a major Aβ species in AD patients· Additionally, Aβ 4-42 was found to be a component of cotton wool plaques in familial AD patients with the V261I PS1 mutation· Aβ 4-42 was discovered as well in amyloid deposits from vascular dementia and familial Danish dementia patients· These observations indicate that Aβ 4-42 may contribute to the development of multiple CNS diseases

ChemicalCAS157884-72-5MW4198.82FormulaC191H294N52O53S
CAS number
157884-72-5
Molecular weight
4198.82
Formula
C191H294N52O53S
Solubility
Soluble in DMSO
Catalogue number
GA20754
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.